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"Sources say the investigation of open source and classified data points to the work in the lab of Dr. Shi Zhengli, who was working on antivirals and immunizations for coronavirus, specifically with bats."

https://www.foxnews.com/politics/us-officials-investigation-coronavirus-wuhan-lab

 

2015

"On the basis of these findings, we synthetically re-derived an infectious full-length SHC014 recombinant virus and demonstrate robust viral replication both in vitro and in vivo."

"SARS-like viruses replicate in human airway cells and produce in vivo pathogenesis."

"Evaluation of available SARS-based immune-therapeutic and prophylactic modalities revealed poor efficacy; both monoclonal antibody and vaccine approaches failed to neutralize and protect from infection with CoVs using the novel spike protein."

https://www.nature.com/articles/nm.3985

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